Tigecycline CAS NO.220620-09-7

Tigecycline is not thought to be extensively metabolised, although some trace metabolites have been identified including a glucuronide, an N-acetyl metabolite, and a tigecycline epimer. Tigecycline is primarily eliminated (about 60
%) via biliary excretion of unchanged drug and some metabolites

Tetracycline in which the hydroxy group at position 5 and the methyl group at position 6 are replaced by hydrogen, and with a dimethylamino substituent and an (N-tert-butylglycyl)amino substituent at positions 7 and 9, respe tively. A glycylcycline antibiotic, it has activity against a broad range of Gram-positive and Gram-negative bacteria, including tetracycline-resistant organisms. It is used for the intravenous treatment of complicated skin and skin structure infections ca sed by susceptible organisms

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